Description

1,3-Bis(4-Fluorobutyl)Urea is a specialized fluorinated urea derivative of significant interest in advanced organic synthesis. This compound serves as a critical building block for the development of novel pharmaceutical intermediates and agrochemicals, offering unique reactivity due to its fluorine-substituted alkyl chains. It is primarily utilized by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate fluorinated motifs into target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated side chains to modulate bioavailability, metabolic stability, and receptor binding affinity.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and pesticides where the introduction of fluorine atoms can enhance biological activity and environmental persistence.
• Fluorinated Polymer Chemistry: Acts as a monomer or cross-linking agent in the synthesis of specialty fluoropolymers with potential applications in coatings, membranes, and high-performance materials.
• Chemical Biology & Probe Development: Employed in the design of molecular probes and tags for studying biological systems, leveraging fluorine as an NMR-active nucleus (19F NMR).
• Organic Synthesis Building Block: Provides a versatile scaffold for further chemical transformations, including nucleophilic substitution and condensation reactions, to create complex molecular architectures.

Basic Information

Product Name	1,3-Bis(4-Fluorobutyl)Urea
CAS No.	542-51-8
Molecular Formula	C9H18F2N2O
Molecular Weight	208.25 g/mol
Synonyms	Urea, N,N'-bis(4-fluorobutyl)-; 1,3-Bis(4-fluorobutyl)urea; N,N'-Di(4-fluorobutyl)urea; 4-Fluorobutyl urea dimer; Bis(4-fluorobutyl)urea; 542-51-8; Urea, 1,3-bis(4-fluorobutyl)-
EINECS	Contact for details

Quality Control

Our 1,3-Bis(4-Fluorobutyl)Urea is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from strong bases and fluorides.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.