Description

2-Chloroacetophenone is a versatile organic intermediate characterized by its reactive carbonyl and chloromethyl groups. This compound matters for its role as a key building block in the synthesis of more complex molecules, particularly in the pharmaceutical and agrochemical sectors. Industries that require it include pharmaceutical manufacturers for active pharmaceutical ingredient (API) synthesis, agrochemical producers for pesticide development, and research institutions exploring novel organic reactions.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various active pharmaceutical ingredients (APIs), including certain analgesics and central nervous system agents.
• Agrochemical Synthesis: Serves as a key building block for manufacturing herbicides, pesticides, and plant growth regulators.
• Fine Chemical Production: Used in the manufacture of dyes, pigments, and other specialty chemicals requiring phenacyl chloride functionality.
• Chemical Research & Development: Employed in organic synthesis laboratories for studying nucleophilic substitution reactions and as a starting material for heterocyclic compounds.
• Fragrance & Flavor Intermediate: Used in the controlled synthesis of certain aroma chemicals, though typically in downstream, modified forms.

Basic Information

Product Name	2-Chloroacetophenone
CAS No.	532-27-4
Molecular Formula	C8H7ClO
Molecular Weight	154.59 g/mol
Synonyms	Phenacyl Chloride; α-Chloroacetophenone; Chloromethyl Phenyl Ketone; 2-Chloro-1-phenylethanone; ω-Chloroacetophenone; CAP; Tear Gas (component); Phenyl Chloromethyl Ketone
EINECS	208-531-1

Quality Control

Our 2-Chloroacetophenone is manufactured under a stringent quality management system. Each batch undergoes rigorous analytical testing, including assay by GC/HPLC and identification by FT-IR, to ensure it meets high-purity standards suitable for synthesis applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Melting Point	54°C - 58°C
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.