Description

Troger's Base is a well-known, rigid V-shaped chiral organic compound with a unique bicyclic structure, serving as a fundamental building block in advanced organic synthesis. Its primary value lies in its utility as a privileged chiral scaffold and ligand for asymmetric catalysis, enabling the production of high-value enantiomerically pure intermediates. This product is essential for research and development laboratories, pharmaceutical companies, and fine chemical manufacturers focused on creating novel catalysts, molecular recognition systems, and specialty materials.

Application

• Asymmetric Catalysis: Employed as a chiral ligand or catalyst framework in enantioselective synthesis reactions.
• Pharmaceutical Intermediates: Used in the synthesis of complex, chiral active pharmaceutical ingredients (APIs) and drug candidates.
• Supramolecular Chemistry: Acts as a key structural component in the design of molecular cages, hosts, and sensors due to its pre-organized, rigid geometry.
• Material Science: Incorporated into the development of chiral polymers, porous organic frameworks, and advanced functional materials.
• Analytical Chemistry: Utilized as a chiral selector or stationary phase modifier in chromatography for enantiomer separation.
• Academic & Industrial Research: Serves as a model compound for studying chirality, host-guest interactions, and reaction mechanisms.

Basic Information

Product Name	Troger's Base
CAS No.	529-81-7
Molecular Formula	C₁₇H₁₈N₂
Molecular Weight	250.34 g/mol
Synonyms	2,8-Dimethyl-6H,12H-5,11-methanodibenzo[b,f][1,5]diazocine; (±)-Troger's Base; DL-Troger's Base; Troeger's Base; Tröger's Base; TB
EINECS	208-463-5

Quality Control

Our Troger's Base is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC for assay and chiral purity, NMR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) documenting all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99:1 d/l ratio
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.