Description

Magnolol is a bioactive biphenolic neolignan compound, a key active constituent derived from the bark of Magnolia officinalis. This compound is valued for its significant pharmacological properties, including potent antioxidant, anti-inflammatory, and neuroprotective activities. It serves as a critical raw material and reference standard for the pharmaceutical, nutraceutical, and cosmetic industries, where high-purity, reliable sourcing is paramount for research, development, and production.

Application

• Pharmaceutical Intermediates & APIs: Used as a key starting material or active pharmaceutical ingredient (API) in formulations targeting inflammation, anxiety, and neurodegenerative conditions.
• Nutraceuticals & Dietary Supplements: Incorporated into supplements for its adaptogenic and antioxidant benefits, supporting overall wellness and stress management.
• Cosmetic & Personal Care Actives: Employed in anti-aging, skin-soothing, and whitening products due to its ability to inhibit melanogenesis and protect against oxidative stress.
• Biomedical Research: Serves as a vital reference standard and biochemical tool in pharmacological, metabolic, and pharmacokinetic studies.
• Traditional Medicine Standardization: Used to standardize extracts of Magnolia bark, ensuring consistent potency and quality in herbal preparations.
• Functional Food & Beverages: Added to health-focused food and drink products to enhance their functional profile with natural bioactive compounds.

Basic Information

Product Name	Magnolol
CAS No.	528-43-8
Molecular Formula	C18H18O2
Molecular Weight	266.33 g/mol
Synonyms	5,5'-Diallyl-2,2'-dihydroxybiphenyl; Magnolol; Honokiol isomer; 2,2'-Dihydroxy-5,5'-diallylbiphenyl; 5,5'-Di-2-propenyl-[1,1'-biphenyl]-2,2'-diol; NSC 293099; Magnolia Bark Extract P.E.
EINECS	208-432-8

Quality Control

Our Magnolol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis, to ensure it meets stringent specifications for pharmaceutical and nutraceutical use. Certificates of Analysis (COA) detailing all test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere); prolonged exposure to air, light, or elevated temperatures should be avoided to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Melting Point	102°C - 105°C
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤10 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.