Description

(1α,2β,3α,4β)-2,4-Diphenyl-1,3-Cyclobutanedicarboxylic Acid is a high-purity, stereochemically defined cyclobutane derivative. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, valued for its rigid, multi-functional structure. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in stereoselective synthesis.
• Agrochemical Research: Building block for creating new herbicides, fungicides, and insecticides with specific stereochemical requirements.
• Ligand & Catalyst Development: Precursor for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Monomer or cross-linking agent for producing specialized polymers with unique thermal or mechanical properties.
• Academic & R&D: Reference standard and starting material for methodological studies in organic and medicinal chemistry.
• Fine Chemical Synthesis: Intermediate in the multi-step production of complex, high-value specialty chemicals.

Basic Information

Product Name	(1α,2β,3α,4β)-2,4-Diphenyl-1,3-Cyclobutanedicarboxylic Acid
CAS No.	528-38-1
Molecular Formula	C18H16O4
Molecular Weight	296.32 g/mol
Synonyms	(1R,2S,3R,4S)-2,4-Diphenylcyclobutane-1,3-dicarboxylic Acid; (1R,2S,3R,4S)-1,3-Dicarboxy-2,4-diphenylcyclobutane; trans,trans-2,4-Diphenyl-1,3-cyclobutanedicarboxylic Acid; (+)-(1R,2S,3R,4S)-2,4-Diphenyl-1,3-cyclobutanedicarboxylic Acid; Cyclobutane-1,3-dicarboxylic acid, 2,4-diphenyl-, (1R,2S,3R,4S)-; DPCBD
EINECS	Contact for details

Quality Control

Our (1α,2β,3α,4β)-2,4-Diphenyl-1,3-Cyclobutanedicarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets exacting standards for research and industrial use. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and other critical specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.