Description

2-[(6R)-3-Methyl-6-Prop-1-En-2-Yl-1-Cyclohex-2-Enyl]-5-Pentyl-Benzene-1,3-Diol (CAS No. 521-37-9) is a high-purity, stereochemically defined cannabinoid derivative of significant interest in advanced research and development. This compound matters as a critical reference standard and a key synthetic intermediate for exploring the structure-activity relationships of cannabinoid analogs. It is primarily needed by pharmaceutical R&D teams, analytical laboratories, and specialty chemical manufacturers focused on neuropharmacology, medicinal chemistry, and the development of novel therapeutic agents.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the quantification and identification of cannabinoid derivatives in analytical methods like HPLC and GC-MS.
• Medicinal Chemistry Research: Serves as a crucial building block or lead compound for synthesizing novel cannabinoid receptor (CB1/CB2) ligands and studying their pharmacological profiles.
• Biochemical Assay Development: Employed in in vitro assays to investigate receptor binding affinity, signal transduction pathways, and enzyme inhibition related to the endocannabinoid system.
• Academic & Institutional Research: Utilized in universities and research institutes for fundamental studies on cannabinoid science, including metabolism, pharmacokinetics, and physiological effects.
• Process Development & Scale-up: Acts as a target molecule or intermediate for process chemistry teams optimizing synthetic routes for potential Active Pharmaceutical Ingredients (APIs).
• Analytical Method Validation: Essential for developing, validating, and calibrating analytical instruments and procedures to ensure accuracy and compliance in cannabinoid testing.

Basic Information

Product Name	2-[(6R)-3-Methyl-6-Prop-1-En-2-Yl-1-Cyclohex-2-Enyl]-5-Pentyl-Benzene-1,3-Diol
CAS No.	521-37-9
Molecular Formula	C21H30O2
Molecular Weight	314.46 g/mol
Synonyms	(-)-Cannabidiol; (-)-CBD; (6aR,10aR)-CBD; Cannabidiol (enantiomer); 2-[(1R,6R)-3-Methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl]-5-pentyl-1,3-benzenediol; (-)-trans-Cannabidiol; 1,3-Benzenediol, 2-[3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl]-5-pentyl-, (1R,6R)-
EINECS	Contact for details

Quality Control

Our 2-[(6R)-3-Methyl-6-Prop-1-En-2-Yl-1-Cyclohex-2-Enyl]-5-Pentyl-Benzene-1,3-Diol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity (by HPLC), and specific rotation is provided with every shipment to guarantee traceability and consistency for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) to minimize oxidation. The container should be kept in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Specific Rotation [α]20/D	-125° to -135° (c=0.5 in ethanol)
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.