Description

(6As)-5,6,6A,7-Tetrahydro-1,9,10-Trimethoxy-6-Methyl-4H-Dibenzo[De,G]Quinolin-2-Ol CAS NO 517-65-7 is a complex, high-purity alkaloid derivative belonging to the aporphine class of organic compounds. This compound is valued for its defined molecular structure, which serves as a critical building block and reference standard in advanced chemical synthesis and analytical research. It is primarily sought by research institutions and pharmaceutical development companies engaged in the study of natural product derivatives, medicinal chemistry, and the development of novel bioactive molecules.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or reference standard in the synthesis and study of novel aporphine-based therapeutic agents.
• Medicinal Chemistry: Used as a scaffold or precursor for structure-activity relationship (SAR) studies to explore new pharmacologically active compounds.
• Analytical Reference Standard: Employed in high-performance liquid chromatography (HPLC), mass spectrometry (MS), and nuclear magnetic resonance (NMR) for method development, calibration, and quality control in laboratories.
• Natural Product Synthesis: Acts as a sophisticated synthetic target or intermediate in the total synthesis of complex natural alkaloids.
• Biochemical Research: Utilized in in-vitro studies to investigate interactions with biological targets, such as enzymes or receptors.
• Academic Research: Provides a valuable compound for university and institutional research projects in organic chemistry and pharmacology.

Basic Information

Product Name	(6As)-5,6,6A,7-Tetrahydro-1,9,10-Trimethoxy-6-Methyl-4H-Dibenzo[De,G]Quinolin-2-Ol
CAS No.	517-65-7
Molecular Formula	C20H23NO4
Molecular Weight	341.40 g/mol
Synonyms	2-Hydroxy-1,9,10-trimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline; Glaucine; (+)-Glaucine; D-Glaucine; NSC 336579; 1,2,9,10-Tetramethoxyaporphine; (6aS)-1,2,9,10-Tetramethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-6-ol
EINECS	208-244-9

Quality Control

Our production of (6As)-5,6,6A,7-Tetrahydro-1,9,10-Trimethoxy-6-Methyl-4H-Dibenzo[De,G]Quinolin-2-Ol adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring full traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.