Description

Cicutoxin CAS NO 505-75-9 is a highly potent, naturally occurring polyyne derivative and neurotoxin. This compound is of significant interest in toxicological research and analytical chemistry for its specific biological activity. It is primarily utilized by research institutions, pharmaceutical development labs, and forensic science organizations. Its precise structure makes it a critical reference standard for the identification and quantification of toxic plant constituents.

Application

• Toxicological Research Standard: Serves as a primary analytical standard for studying acute neurotoxicity mechanisms and dose-response relationships.
• Phytochemical Reference Material: Used in laboratories for the identification, isolation, and quantification of toxic components in plants of the Cicuta (water hemlock) genus.
• Forensic Analysis: Employed as a certified reference material in forensic toxicology to confirm suspected plant-based poisonings in clinical or post-mortem investigations.
• Biochemical Pathway Studies: Utilized in research to investigate its interaction with the central nervous system, particularly its effect on GABA receptors and neuronal excitation.
• Method Development & Validation: Acts as a key compound for developing and validating sensitive analytical methods such as HPLC, LC-MS, and GC-MS for toxin detection.
• Safety & Regulatory Testing: Used by environmental and agricultural agencies to establish safety profiles and contamination limits in relevant matrices.

Basic Information

Product Name	Cicutoxin
CAS No.	505-75-9
Molecular Formula	C17H22O2
Molecular Weight	258.36 g/mol
Synonyms	(8E,10E,12E)-Heptadeca-8,10,12-triene-4,6-diyne-1,14-diol; 1,14-Dihydroxy-(8E,10E,12E)-heptadeca-8,10,12-triene-4,6-diync; Oenanthotoxin (related compound); Water Hemlock Toxin; Cicuta Toxin
EINECS	Contact for details

Quality Control

Our Cicutoxin is produced and handled under strict quality management protocols to ensure the highest standards of purity and consistency for research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles. We ensure traceability and compliance with relevant standards for high-purity reference materials. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to minimize oxidation and degradation. The container should be kept in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.