Description

4-Aminopyridine is a potent and selective potassium channel blocker with significant pharmacological activity. This compound is a critical intermediate and active pharmaceutical ingredient (API) in the development of treatments for neurological conditions, particularly multiple sclerosis. It serves essential roles for pharmaceutical manufacturers, research institutions, and fine chemical synthesis specialists focused on neuropharmacology and ion channel research.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of advanced drug candidates targeting potassium channels.
• Neurological Research: Used as a reference standard and tool compound in preclinical studies for conditions like multiple sclerosis (MS) and spinal cord injury.
• API Manufacturing: Serves as the active pharmaceutical ingredient in the production of approved symptomatic therapies for MS.
• Biochemical Research: Employed in electrophysiology and neuroscience laboratories to study synaptic transmission and neuronal excitability.
• Fine Chemical Synthesis: A versatile aminopyridine derivative used in organic synthesis to create more complex molecular structures.
• Veterinary Medicine: Investigated for applications in treating certain neurological conditions in animals.

Basic Information

Product Name	4-Aminopyridine
CAS No.	504-24-5
Molecular Formula	C5H6N2
Molecular Weight	94.11 g/mol
Synonyms	4-AP; Fampridine; Dalfampridine; 4-Pyridinamine; γ-Aminopyridine; Pymadine; Avitrol (bird repellent); NSC 13872; UNII-BH3B64OKL9
EINECS	207-987-9

Quality Control

Our 4-Aminopyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identification by FT-IR and NMR, to ensure it meets exacting standards for pharmaceutical and research use. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with specified purity grades.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥98.0% - 102.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.