Description

n-Nitrosodiethylamine is a nitrosamine compound of significant industrial and research importance. This chemical is primarily utilized as a critical reference standard and reagent in analytical chemistry and toxicological studies. It serves essential roles for laboratories and manufacturers in the pharmaceutical, environmental, and chemical research sectors requiring precise analytical controls.

Application

• Analytical Reference Standard: Primary use as a certified reference material (CRM) for the calibration of analytical instruments like GC-MS and HPLC in nitrosamine testing.
• Toxicology Research: Employed as a model carcinogen in biochemical and genetic toxicology studies to understand mechanisms of action and assess mutagenicity.
• Pharmaceutical Impurity Testing: Critical for method development and validation in detecting and quantifying nitrosamine impurities (e.g., NDMA) in active pharmaceutical ingredients (APIs) and drug products to meet regulatory standards (e.g., FDA, EMA).
• Environmental Analysis: Used in research and monitoring to detect and quantify nitrosamine contamination in water, soil, and industrial waste.
• Chemical Research: Serves as a reagent and building block in organic synthesis research for studying nitrosation reactions and developing novel compounds.
• Quality Control Laboratories: Essential for internal quality control and proficiency testing in labs ensuring the accuracy of nitrosamine analysis across various matrices.

Basic Information

Product Name	n-Nitrosodiethylamine
CAS No.	55-18-5
Molecular Formula	C4H10N2O
Molecular Weight	102.14 g/mol
Synonyms	N-Nitrosodiethylamine; Diethylnitrosamine; NDEA; N-Nitroso-N-ethylethanamine; N-Ethyl-N-nitrosoethanamine; Nitrous diethylamide; DEN; Diethylnitrosamine
EINECS	200-226-1

Quality Control

Our n-Nitrosodiethylamine is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including identity confirmation by FT-IR and NMR, and purity assessment by chromatographic methods (HPLC/GC), to ensure it meets the high standards required for research and analytical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming batch-specific results for identity, purity, and related substances.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its light-sensitive nature and propensity to be easily oxidized, it is recommended to store the material under an inert atmosphere (e.g., nitrogen) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to orange liquid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.