Description

Plerixafor Hexa(Trifluoroacetate) is a high-purity salt form of the CXCR4 chemokine receptor antagonist Plerixafor. This compound is critical for research and development in the life sciences sector, particularly for applications requiring precise biological activity. It is primarily utilized by pharmaceutical researchers, biotechnology companies, and academic institutions engaged in hematopoiesis studies, stem cell mobilization research, and oncology drug discovery.

Application

• Stem Cell Mobilization Research: A key reagent in preclinical studies investigating the mechanism of hematopoietic stem cell (HSC) release from bone marrow.
• Oncology & Cancer Research: Used to study the role of the CXCR4/SDF-1 axis in tumor metastasis, angiogenesis, and cancer cell proliferation.
• Pharmacological Reference Standard: Serves as a certified reference material (CRM) for analytical method development, validation, and quality control in pharmaceutical manufacturing.
• Biochemical Assay Development: Essential for developing high-throughput screening (HTS) assays to identify novel CXCR4 antagonists or modulators.
• Cell Culture & In Vitro Studies: Applied in cell-based experiments to block CXCR4 receptor signaling and study downstream biological effects.
• API Intermediate Synthesis: Used as a key intermediate in the synthesis of Plerixafor active pharmaceutical ingredient (API) under current Good Manufacturing Practices (cGMP).

Basic Information

Product Name	Plerixafor Hexa(Trifluoroacetate)
CAS No.	4069393-93-3
Molecular Formula	C₃₂H₅₄N₈O₈ • xC₂HF₃O₂ (Contact for exact stoichiometry)
Molecular Weight	Contact for details
Synonyms	AMD3100 Hexa(Trifluoroacetate); 1,1'-[1,4-Phenylenebis(methylene)]bis[1,4,8,11-tetraazacyclotetradecane] Hexakis(2,2,2-trifluoroacetate); JM 3100 Hexa(TFA) Salt; Plerixafor Octahydrochloride Analog; CXCR4 Antagonist Salt; Mozobil Impurity Salt; bicyclam derivative hexa(trifluoroacetate)
EINECS	Contact for details

Quality Control

Our Plerixafor Hexa(Trifluoroacetate) is manufactured under strict quality systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent controls for residual solvents and impurities. A detailed Certificate of Analysis (COA) providing batch-specific data is supplied with every shipment to ensure traceability and compliance with research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccated or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95.0% (Area Percent)
Water Content (KF)	≤5.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.