Description

Plerixafor is a selective antagonist of the CXCR4 chemokine receptor, functioning as a hematopoietic stem cell mobilizer. This compound is of critical importance in the pharmaceutical and biotechnology sectors for enabling the collection of stem cells from peripheral blood. It is primarily required by manufacturers of active pharmaceutical ingredients (APIs), clinical research organizations, and companies developing advanced cell and gene therapies.

Application

• Active Pharmaceutical Ingredient (API) in stem cell mobilization therapies.
• Key component in the manufacturing of autologous hematopoietic stem cell transplantation products for patients with non-Hodgkin's lymphoma and multiple myeloma.
• Research and development of novel oncology and immunology treatments targeting the CXCR4 pathway.
• Pre-clinical and clinical studies investigating stem cell biology and mobilization mechanisms.
• Production of high-purity reference standards for analytical and quality control laboratories.
• Development of combination therapies in regenerative medicine.

Basic Information

Item	Detail
Product Name	Plerixafor
CAS No.	110078-46-1
Molecular Formula	C28H54N8
Molecular Weight	502.78 g/mol
Synonyms	AMD 3100; JM 3100; 1,1'-[1,4-Phenylenebis(methylene)]bis[1,4,8,11-tetraazacyclotetradecane]; Mozobil (trade name); 1,4-Bis(1,4,8,11-tetraazacyclotetradecan-1-ylmethyl)benzene; Cyclam, 1,1'-[1,4-phenylenebis(methylene)]bis-; NSC 709130; Bicyclam JM3100
EINECS	Contact for details

Quality Control

Our Plerixafor is manufactured under strict quality management systems to ensure it meets the stringent requirements for pharmaceutical intermediates and APIs. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant ICH guidelines and can supply material suitable for GMP applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.