Description

(S)-Boc-3-Methoxy-β-Phe-Oh is a high-purity, non-natural amino acid derivative featuring a chiral center and a tert-butoxycarbonyl (Boc) protecting group. This compound matters as a critical chiral building block for the synthesis of complex peptides and peptidomimetics, enabling precise control over stereochemistry in pharmaceutical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for applications in drug discovery and development.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic peptides and small molecule drugs.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate a methoxy-substituted phenylalanine residue with defined (S)-configuration.
• Protease Inhibitor Development: Serves as a core structural component in the design and synthesis of protease inhibitors targeting various diseases.
• Chemical Biology Research: Employed in the study of protein-protein interactions and the creation of labeled or modified peptide probes.
• Process Chemistry: Utilized in the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs).
• Academic Research: A valuable reagent for universities and research institutes exploring new synthetic methodologies and bio-active compounds.

Basic Information

Product Name	(S)-Boc-3-Methoxy-β-Phe-Oh
CAS No.	499995-77-6
Molecular Formula	C15H21NO5
Molecular Weight	295.33 g/mol
Synonyms	(S)-3-(3-Methoxyphenyl)-2-((tert-butoxycarbonyl)amino)propanoic acid; Boc-3-MeO-β-homoPhe-OH; (S)-2-(tert-Butoxycarbonylamino)-3-(3-methoxyphenyl)propanoic acid; Boc-L-3-Methoxy-β-homophenylalanine; N-Boc-3-Methoxy-β-homophenylalanine; tert-Butyl (S)-(1-carboxy-2-(3-methoxyphenyl)ethyl)carbamate; N-(tert-Butoxycarbonyl)-3-methoxy-β-homophenylalanine
EINECS	Contact for details

Quality Control

Our (S)-Boc-3-Methoxy-β-Phe-Oh is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity and chiral integrity, meeting the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) providing detailed specifications for identity, purity, and chiral excess are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.