Description

5-(Bromomethyl)-1-Methyl-1H-1,2,3-Benzotriazole is a versatile benzotriazole derivative, a key synthetic intermediate prized for its reactive bromomethyl functional group. This compound is essential for introducing the 1-methylbenzotriazole moiety into more complex molecular architectures via nucleophilic substitution or cross-coupling reactions. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other heterocyclic-based therapeutics.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides where the benzotriazole scaffold confers specific biological activity.
• Material Science & Polymer Chemistry: Serves as a functional monomer or cross-linking agent for creating polymers with specialized properties, such as UV stabilizers or corrosion inhibitors.
• Ligand & Catalyst Development: Employed in the preparation of N-donor ligands for transition metal catalysis, useful in various organic transformations.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D labs exploring new synthetic pathways and heterocyclic chemistry.
• Fine Chemical Production: Integral to the multi-step synthesis of complex fine chemicals and specialty dyes.

Basic Information

Product Name	5-(Bromomethyl)-1-Methyl-1H-1,2,3-Benzotriazole
CAS No.	499770-76-2
Molecular Formula	C8H8BrN3
Molecular Weight	226.07 g/mol
Synonyms	1-Methyl-5-(bromomethyl)-1H-benzotriazole; 1-Methyl-1H-benzotriazol-5-ylmethyl bromide; 5-(Bromomethyl)-1-methylbenzotriazole; 1H-Benzotriazole, 5-(bromomethyl)-1-methyl-; 1-Methyl-5-bromomethylbenzotriazole
EINECS	Contact for details

Quality Control

Our production of 5-(Bromomethyl)-1-Methyl-1H-1,2,3-Benzotriazole adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure consistency and reliability for your critical syntheses. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key specifications such as assay purity and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere or in a dry environment to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.