Description

3,5-Cyclohexadiene-1,2-Diol, 3-[(R)-(1-Methylethyl)Sulfinyl]-, (1S,2S)- (9Ci) CAS NO 499202-01-6 is a high-purity, chiral sulfoxide derivative of a cyclohexadienediol, serving as a sophisticated building block in asymmetric synthesis. Its defined stereochemistry makes it a valuable intermediate for constructing complex molecules with high enantiomeric purity, which is critical for efficacy and safety in advanced applications. This compound is primarily targeted at research and development laboratories and production facilities in the pharmaceutical and fine chemical sectors, where precise stereochemical control is paramount.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug candidates.
• Asymmetric Catalyst Ligand Precursor: Used in the synthesis of specialized ligands for transition metal catalysis, enabling enantioselective transformations.
• Fine Chemical Synthesis: Building block for creating complex natural product analogs and other high-value specialty chemicals with specific stereocenters.
• Academic & Industrial R&D: Employed in methodological research for new synthetic routes and the study of stereoselective reactions.
• Process Chemistry Development: Serves as a reference standard or intermediate in scaling up synthetic pathways from laboratory to pilot plant scale.

Basic Information

Product Name	3,5-Cyclohexadiene-1,2-Diol, 3-[(R)-(1-Methylethyl)Sulfinyl]-, (1S,2S)- (9Ci)
CAS No.	499202-01-6
Molecular Formula	C9H14O3S
Molecular Weight	202.27 g/mol
Synonyms	(1S,2S)-3-[(R)-Isopropylsulfinyl]cyclohexa-3,5-diene-1,2-diol; (1S,2S)-3-[(R)-(1-Methylethyl)sulfinyl]-3,5-cyclohexadiene-1,2-diol; (1S,2S,3R)-3-(Isopropylsulfinyl)cyclohexa-4,6-diene-1,2-diol; Chiral Sulfinyl Dihydrodiol; Isopropylsulfinyl Cyclohexadienediol; (1S,2S)-3-[(R)-Propan-2-ylsulfinyl]cyclohexa-3,5-diene-1,2-diol
EINECS	Contact for details

Quality Control

Every batch of our 3,5-Cyclohexadiene-1,2-Diol, 3-[(R)-(1-Methylethyl)Sulfinyl]-, (1S,2S)- (9Ci) is produced and controlled under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, and chiral analysis to ensure identity, purity, and enantiomeric excess meet exacting standards. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.