Description

2(1H)-Naphthalenone, Octahydro-4,8A-Dihydroxy-4A-(Hydroxymethyl)-, (4R,4Ar,8As)-Rel- (9Ci) is a complex, stereochemically defined polyhydroxylated decalin derivative that serves as a valuable chiral building block in advanced organic synthesis. Its intricate structure, featuring multiple hydroxyl groups and a defined relative stereochemistry, makes it a critical intermediate for constructing complex natural product analogs and pharmaceutical scaffolds. This compound is primarily sought after by research institutions and development laboratories in the pharmaceutical, agrochemical, and fine chemical sectors for the synthesis of novel bioactive molecules.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in classes like steroids, terpenoids, and complex polycyclic molecules.
• Agrochemical Research: Used as a precursor in the synthesis of novel, stereospecific pesticides, herbicides, and plant growth regulators.
• Fine Chemical Synthesis: Serves as a sophisticated starting material or intermediate for producing specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic & R&D: Employed in university and corporate research laboratories for methodological studies in asymmetric synthesis, total synthesis, and catalysis.
• Material Science Precursor: Potential use in developing chiral ligands for catalysts or advanced polymeric materials with specific structural motifs.

Basic Information

Product Name	2(1H)-Naphthalenone, Octahydro-4,8A-Dihydroxy-4A-(Hydroxymethyl)-, (4R,4Ar,8As)-Rel- (9Ci)
CAS No.	498575-30-7
Molecular Formula	C11H18O4
Molecular Weight	214.26 g/mol
Synonyms	rel-(4R,4aR,8aS)-Octahydro-4,8a-dihydroxy-4a-(hydroxymethyl)-2(1H)-naphthalenone; (4R,4aR,8aS)-4,8a-Dihydroxy-4a-(hydroxymethyl)decahydro-2H-naphthalen-2-one; Octahydro-4,8a-dihydroxy-4a-(hydroxymethyl)-, (4R,4aR,8aS)-rel-2(1H)-Naphthalenone; A polyhydroxylated decalinone derivative; Chiral decalin building block
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality protocols to ensure batch-to-batch consistency and high purity, critical for sensitive synthetic applications. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral purity, and impurity profile is provided with every shipment. We support cGMP and ISO 9001 compliant manufacturing standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.