Description

Methyl 2-(4,5-Dimethoxy-2-((6-Methyl(1,2,3,4-Tetrahydroquinolyl))Sulfonyl)Phenyl)Acetate is a high-purity, advanced pharmaceutical intermediate characterized by its complex sulfonamide and tetrahydroquinoline structure. This compound matters as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and cardiovascular disorders. It is primarily needed by R&D laboratories, process development chemists, and manufacturers in the pharmaceutical and biotechnology industries for the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug molecules, especially those with sulfonamide pharmacophores.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry: Serves as a standardized building block for scaling up synthetic routes under current Good Manufacturing Practice (cGMP) conditions.
• API Synthesis: Integral in constructing the core scaffold of potential APIs targeting neurological and cardiovascular pathways.
• Chemical Biology: Can be utilized as a probe or tool compound in biochemical assays to study enzyme inhibition or receptor binding.

Basic Information

Product Name	Methyl 2-(4,5-Dimethoxy-2-((6-Methyl(1,2,3,4-Tetrahydroquinolyl))Sulfonyl)Phenyl)Acetate
CAS No.	497060-19-2
Molecular Formula	C21H25NO6S
Molecular Weight	419.49 g/mol
Synonyms	Methyl 2-[4,5-dimethoxy-2-[(6-methyl-1,2,3,4-tetrahydroquinolin-1-yl)sulfonyl]phenyl]acetate; 1-[(4,5-Dimethoxy-2-{2-[methoxycarbonyl]ethyl}phenyl)sulfonyl]-6-methyl-1,2,3,4-tetrahydroquinoline; 497060-19-2; Methyl (4,5-dimethoxy-2-{[(6-methyl-3,4-dihydro-2H-quinolin-1-yl)]sulfonyl}phenyl)acetate
EINECS	Contact for details

Quality Control

Our production of Methyl 2-(4,5-Dimethoxy-2-((6-Methyl(1,2,3,4-Tetrahydroquinolyl))Sulfonyl)Phenyl)Acetate adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our quality systems are designed to support development through to commercial scale, meeting the exacting standards required for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.