Description

2-Quinolin-2-Yl-1-(4-Trifluoromethylphenyl)Ethanol is a high-purity, advanced pharmaceutical intermediate characterized by its unique quinoline and trifluoromethylphenyl functional groups. This compound matters as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for therapeutic agents targeting the central nervous system and oncology. Pharmaceutical R&D laboratories and fine chemical manufacturers need this precise intermediate to develop next-generation drug candidates with enhanced efficacy and metabolic stability.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, especially those with quinoline-based scaffolds.
• Organic Synthesis Building Block: Used in research and development for constructing more complex heterocyclic compounds via its reactive alcohol and aromatic groups.
• Agrochemical Research: Serves as a starting material for developing new crop protection agents and pesticides due to its structural motifs.
• Material Science: Investigated for use in the development of specialty chemicals and advanced organic materials, including ligands for catalysis.
• Academic & Contract Research: Utilized in university and CRO (Contract Research Organization) settings for medicinal chemistry programs and methodological studies.

Basic Information

Product Name	2-Quinolin-2-Yl-1-(4-Trifluoromethylphenyl)Ethanol
CAS No.	496947-30-9
Molecular Formula	C₁₈H₁₄F₃NO
Molecular Weight	317.31 g/mol
Synonyms	1-(4-(Trifluoromethyl)phenyl)-2-(quinolin-2-yl)ethanol; 2-Quinolin-2-yl-1-[4-(trifluoromethyl)phenyl]ethanol; α-(2-Quinolyl)-4-(trifluoromethyl)benzenemethanol; 2-(2-Hydroxy-2-[4-(trifluoromethyl)phenyl]ethyl)quinoline; (RS)-2-Quinolin-2-yl-1-(4-trifluoromethylphenyl)ethanol; Benzenemethanol, α-(2-quinolyl)-4-(trifluoromethyl)-; CAS 496947-30-9
EINECS	Contact for details

Quality Control

Our 2-Quinolin-2-Yl-1-(4-Trifluoromethylphenyl)Ethanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product should be kept under an inert atmosphere if long-term storage is required to prevent potential degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.