Description

(2E)-3-(4'-Hydroxy-3'-Tricyclo[3.3.1.13,7]Dec-1-Yl[1,1'-Biphenyl]-4-Yl)-2-Propenoic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique adamantane and biphenyl-based molecular architecture. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting complex disease pathways. It is primarily sought after by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in developing next-generation therapeutics.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, especially in medicinal chemistry research.
• Organic Synthesis Building Block: Used in complex multi-step organic reactions, leveraging its rigid adamantane core to influence molecular conformation and stability.
• Research & Development (R&D): Employed in academic and industrial labs for studying structure-activity relationships (SAR) and developing new chemical entities.
• Material Science Research: Potential use in the development of specialty polymers or advanced organic materials due to its bulky, aromatic structure.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	(2E)-3-(4'-Hydroxy-3'-Tricyclo[3.3.1.13,7]Dec-1-Yl[1,1'-Biphenyl]-4-Yl)-2-Propenoic Acid
CAS No.	496868-77-0
Molecular Formula	C25H26O3
Molecular Weight	374.47 g/mol
Synonyms	(2E)-3-[4'-Hydroxy-3'-(1-adamantyl)[1,1'-biphenyl]-4-yl]acrylic acid; 3-(4'-Hydroxy-3'-tricyclo[3.3.1.13,7]dec-1-ylbiphenyl-4-yl)acrylic acid; (E)-3-(4'-Hydroxy-3'-adamantan-1-ylbiphenyl-4-yl)acrylic acid; Adamantylbiphenyl acrylic acid derivative; 496868-77-0; BRN 8285136; LS-1965
EINECS	Contact for details

Quality Control

Our (2E)-3-(4'-Hydroxy-3'-Tricyclo[3.3.1.13,7]Dec-1-Yl[1,1'-Biphenyl]-4-Yl)-2-Propenoic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets exacting specifications for pharmaceutical R&D. Certificates of Analysis (COA) detailing all test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to protect the contents from moisture and atmospheric contamination.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.