Description

8-Cyano-4-Hydroxy-Quinoline-2-Carboxylic Acid is a high-purity, multi-functional quinoline derivative serving as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring cyano, hydroxyl, and carboxylic acid functional groups, makes it a versatile intermediate for creating complex molecules with tailored properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for developing kinase inhibitors, antimicrobial agents, and other therapeutic molecules.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators.
• Coordination Chemistry & Chelating Agent: Serves as a ligand for metal ions in catalytic systems and for the preparation of metal-organic frameworks (MOFs).
• Fluorescent Dye & Sensor Development: Acts as a core structure for synthesizing advanced fluorescent probes and chemosensors due to the quinoline scaffold.
• Material Science Research: Building block for organic electronic materials, such as components for OLEDs or conductive polymers.
• Chemical Research & Process Development: A valuable standard and intermediate for method development and scaling in process chemistry.

Basic Information

Product Name	8-Cyano-4-Hydroxy-Quinoline-2-Carboxylic Acid
CAS No.	495409-74-0
Molecular Formula	C₁₁H₆N₂O₃
Molecular Weight	214.18 g/mol
Synonyms	8-Cyano-4-hydroxyquinoline-2-carboxylic acid; 2-Quinolinecarboxylic acid, 8-cyano-4-hydroxy-; 4-Hydroxy-8-cyanoquinoline-2-carboxylic acid; 8-Cyano-4-hydroxy-2-quinolinecarboxylic acid; 495409-74-0; 8-CN-4-OH-QA-2-COOH
EINECS	Contact for details

Quality Control

Our 8-Cyano-4-Hydroxy-Quinoline-2-Carboxylic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with key parameters including assay, impurity profile, and residual solvents. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP-compliant production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids. The compound may be light-sensitive; store away from light.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.