Description

1-(Phenylsulfonyl)Piperidine-3-Carbohydrazide is a specialized organic building block featuring a piperidine core functionalized with both a phenylsulfonyl group and a carbohydrazide moiety. This unique structure makes it a valuable intermediate for the synthesis of complex molecules in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working on novel active ingredients. The compound, identified by CAS number 494825-75-1, requires careful handling due to its sensitivity.

Application

• Pharmaceutical Intermediate: Key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders or enzyme inhibitors.
• Agrochemical Research: Serves as a precursor in the synthesis of novel herbicides, fungicides, or insecticides, leveraging its heterocyclic scaffold.
• Chemical Biology Probe Development: Used to create tool compounds for studying biological pathways, where the sulfonyl and hydrazide groups allow for specific conjugation or binding.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds at various scales.
• Academic Research: Utilized in university and institutional labs for methodological studies in organic synthesis and heterocyclic chemistry.
• Material Science Precursor: Potential starting material for the synthesis of specialty polymers or ligands for catalytic systems.

Basic Information

Product Name	1-(Phenylsulfonyl)Piperidine-3-Carbohydrazide
CAS No.	494825-75-1
Molecular Formula	C12H17N3O3S
Molecular Weight	283.35 g/mol
Synonyms	1-(Benzenesulfonyl)piperidine-3-carbohydrazide; 3-Hydrazinylcarbonyl-1-(phenylsulfonyl)piperidine; Piperidine-3-carbohydrazide, 1-(phenylsulfonyl)-; 1-Phenylsulfonylpiperidine-3-carboxylic acid hydrazide; 1-(Phenylsulfonyl)-3-piperidinecarbohydrazide; PS-PCH
EINECS	Contact for details

Quality Control

Our 1-(Phenylsulfonyl)Piperidine-3-Carbohydrazide is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications. Our quality system is designed to support cGMP (current Good Manufacturing Practice) standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.