Description

1,4,7,10-Tetraazacyclododecane, 2,5,8,11-Tetramethyl is a high-purity, substituted cyclen derivative, a key macrocyclic ligand in coordination chemistry. This compound is valued for its strong and selective chelating properties towards various metal ions, enabling the creation of stable, functional complexes. It is primarily utilized by researchers and manufacturers in the pharmaceutical, diagnostic, and advanced materials sectors for developing catalysts, imaging agents, and metal-based therapeutics.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor for synthesizing novel metal-based drugs and targeted therapeutic agents.
• MRI Contrast Agent Development: Used as a chelating scaffold for gadolinium and other lanthanide ions to create next-generation contrast media.
• Catalyst Ligand: Functions as a sophisticated ligand in homogeneous catalysis for organic synthesis and polymerization processes.
• Radiopharmaceuticals: Chelates radioisotopes (e.g., Copper-64, Gallium-68) for use in Positron Emission Tomography (PET) imaging and targeted radiotherapy.
• Chemical Sensor Fabrication: Incorporated into sensor materials for the selective detection of specific metal ions or small molecules.
• Advanced Material Synthesis: Employed in the design of metal-organic frameworks (MOFs) and functional nanomaterials.
• Research & Development: A vital tool in academic and industrial R&D for studying coordination chemistry and developing new metal complexes.

Basic Information

Product Name	1,4,7,10-Tetraazacyclododecane, 2,5,8,11-Tetramethyl
CAS No.	494751-27-8
Molecular Formula	C12H28N4
Molecular Weight	228.38 g/mol
Synonyms	2,5,8,11-Tetramethyl-1,4,7,10-tetraazacyclododecane; Tetramethyl Cyclen; 2,5,8,11-Tetramethyl-cyclen; TM-cyclen; 1,4,7,10-Tetraazacyclododecane, 2,5,8,11-tetramethyl-; 2,5,8,11-Tetramethyl-[12]aneN4; 2,5,8,11-Me4-cyclen
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques to guarantee identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for purity, assay, and impurity profiles are available upon request. We adhere to strict quality management protocols to support applications in sensitive fields like pharmaceutical research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.