Description

2-Chloroethyl α-L-Fucopyranoside is a specialized carbohydrate derivative, a glycoside where a 2-chloroethyl group is linked to the anomeric carbon of the rare sugar L-fucose. This compound matters as a crucial synthetic intermediate and biochemical tool, enabling the study and modulation of fucose-specific biological processes. It is primarily needed by researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors for applications in glycobiology, drug discovery, and the development of novel therapeutics and probes.

Application

• Glycobiology Research: A key building block for the chemical and enzymatic synthesis of complex oligosaccharides, glycoconjugates, and glycomimetics to study fucose-mediated biological recognition.
• Pharmaceutical Intermediates: Serves as a precursor in the synthesis of potential drug candidates, particularly those targeting inflammation, cancer, and infectious diseases where fucosylation plays a role.
• Enzyme Substrate/Inhibitor Development: Used to develop substrates or inhibitors for fucosyltransferases and other glycosyl-processing enzymes for mechanistic and therapeutic studies.
• Diagnostic Probe Synthesis: Employed in the creation of labeled probes (e.g., fluorescent, biotinylated) for detecting and imaging fucose-binding proteins like lectins.
• Bioconjugation and Material Science: The reactive chloroethyl group allows for further functionalization, enabling its attachment to surfaces, polymers, or proteins for creating bioactive materials.
• Standards and Reference Materials: Provides a high-purity standard for analytical methods such as HPLC and MS in quality control and metabolic pathway analysis.

Basic Information

Product Name	2-Chloroethyl α-L-Fucopyranoside
CAS No.	491593-36-3
Molecular Formula	C8H15ClO5
Molecular Weight	226.65 g/mol
Synonyms	2-Chloroethyl α-L-fucopyranoside; α-L-Fucopyranoside, 2-chloroethyl; 2-Chloroethyl α-L-fucoside; 1-O-(2-Chloroethyl)-α-L-fucopyranose; (2R,3S,4S,5R,6S)-2-(Hydroxymethyl)-6-((2-chloroethoxy)methyl)tetrahydro-2H-pyran-3,4,5-triol; L-Fucose, 2-chloroethyl glycoside
EINECS	Contact for details

Quality Control

Our 2-Chloroethyl α-L-Fucopyranoside is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and specific tests for residual solvents and moisture. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake. Handle and store in accordance with good laboratory practices.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.