Description

α-(4-Bromophenyl)1-Pyrrolidineacetic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its specific brominated aromatic and pyrrolidine acetic acid structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) and other fine chemicals, offering a versatile building block for medicinal chemistry. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its bromophenyl moiety for biological activity.
• Ligand and Catalyst Synthesis: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and receptor interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic & Industrial R&D: Used in research laboratories for method development and exploring new synthetic pathways.

Basic Information

Product Name	α-(4-Bromophenyl)1-Pyrrolidineacetic Acid
CAS No.	490027-02-6
Molecular Formula	C₁₂H₁₄BrNO₂
Molecular Weight	284.15 g/mol
Synonyms	1-Pyrrolidineacetic acid, α-(4-bromophenyl)-; 2-(4-Bromophenyl)-2-(pyrrolidin-1-yl)acetic acid; (4-Bromophenyl)(pyrrolidin-1-yl)acetic acid; 490027-02-6; α-(4-Bromophenyl)-1-pyrrolidineacetic acid; 2-(4-Bromophenyl)-2-(1-pyrrolidinyl)acetic acid
EINECS	Contact for details

Quality Control

Our α-(4-Bromophenyl)1-Pyrrolidineacetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting our customers' regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.