Description

6-Bromo-2-(3-Isobutoxy-Phenyl)-Quinoline-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the research and development of novel therapeutic agents, particularly in the fields of oncology and anti-inflammatory treatments. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions engaged in medicinal chemistry and drug discovery programs. The compound's specific bromo and carboxylic acid functionalities make it a versatile building block for targeted molecular synthesis.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel quinoline-based active pharmaceutical ingredients (APIs) targeting specific biological pathways.
• Medicinal Chemistry Research: Used as a core scaffold or building block for structure-activity relationship (SAR) studies in drug discovery projects.
• Kinase Inhibitor Development: Employed in the research and synthesis of potential kinase inhibitors for cancer and inflammatory diseases.
• Fine Chemical Synthesis: Acts as a specialized intermediate for creating complex, high-value organic molecules in custom synthesis and contract manufacturing.
• Biochemical Tool Compound: May be used in biochemical assays to study enzyme interactions or cellular processes.
• Academic & Institutional Research: Utilized in universities and research institutes for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	6-Bromo-2-(3-Isobutoxy-Phenyl)-Quinoline-4-Carboxylic Acid
CAS No.	489451-29-8
Molecular Formula	C₂₁H₂₀BrNO₃
Molecular Weight	414.29 g/mol
Synonyms	6-Bromo-2-(3-isobutoxyphenyl)quinoline-4-carboxylic acid; 2-(3-Isobutoxyphenyl)-6-bromoquinoline-4-carboxylic acid; 4-Quinolinecarboxylic acid, 6-bromo-2-[3-(2-methylpropoxy)phenyl]-; 489451-29-8; 6-Bromo-2-(3-isobutoxy-phenyl)-quinoline-4-carboxylic acid; Quinoline-4-carboxylic acid, 6-bromo-2-(3-isobutoxyphenyl)-
EINECS	Contact for details

Quality Control

Our 6-Bromo-2-(3-Isobutoxy-Phenyl)-Quinoline-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.