Description

Ethyl 6-Bromo-2-(tert-Butyl)-5-((2-Methylallyl)Oxy)Benzofuran-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate with a complex benzofuran core structure. This compound matters as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), enabling research and development in targeted therapeutic areas. It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug candidates, particularly those targeting specific enzyme pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Organic Synthesis Building Block: The reactive bromo and alkoxy functional groups make it valuable for constructing more complex heterocyclic systems.
• Process Chemistry Development: Employed in scaling up synthetic routes for potential new chemical entities (NCEs) under Good Manufacturing Practice (GMP) conditions.
• Academic & Institutional Research: Utilized in universities and research institutes for exploring new synthetic methodologies and chemical biology.
• Contract Research & Manufacturing (CRAM): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.

Basic Information

Product Name	Ethyl 6-Bromo-2-(tert-Butyl)-5-((2-Methylallyl)Oxy)Benzofuran-3-Carboxylate
CAS No.	488841-38-9
Molecular Formula	C19H23BrO4
Molecular Weight	395.29 g/mol
Synonyms	Ethyl 6-bromo-2-tert-butyl-5-(2-methylprop-2-en-1-yloxy)-1-benzofuran-3-carboxylate; 6-Bromo-2-(tert-butyl)-5-[(2-methyl-2-propen-1-yl)oxy]-3-benzofurancarboxylic Acid Ethyl Ester; 3-Benzofurancarboxylic acid, 6-bromo-2-(1,1-dimethylethyl)-5-[(2-methyl-2-propen-1-yl)oxy]-, ethyl ester; Ethyl 6-Bromo-2-(tert-Butyl)-5-(2-Methylallyloxy)Benzofuran-3-Carboxylate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for advanced intermediates. Every batch is characterized using modern analytical techniques, including HPLC, GC, NMR, and mass spectrometry, to confirm identity, purity, and consistency. Certificates of Analysis (COA) are provided with each shipment, detailing all relevant specifications. We adhere to a quality management system and can support development under controlled conditions suitable for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.