Description

n-(3-Chloro-Quinoxalin-2-Yl)-4-Fluoro-Benzenesulfonamide CAS NO 488744-02-1 is a high-purity, advanced pharmaceutical intermediate characterized by its unique quinoxaline-sulfonamide hybrid structure. This compound is critical for research and development in medicinal chemistry, offering a versatile scaffold for creating novel bioactive molecules. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents, particularly in the areas of oncology and infectious diseases.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity.
• Kinase Inhibitor Development: A potential precursor in the synthesis of small molecule inhibitors for tyrosine kinases and other enzyme targets.
• Antimicrobial Agent Research: Explored for the development of new antibacterial or antifungal agents due to the quinoxaline moiety's bioactive properties.
• Chemical Biology Probes: Utilized in the creation of molecular probes to study biological processes and identify new drug targets.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	n-(3-Chloro-Quinoxalin-2-Yl)-4-Fluoro-Benzenesulfonamide
CAS No.	488744-02-1
Molecular Formula	C14H9ClFN3O2S
Molecular Weight	337.75 g/mol
Synonyms	4-Fluoro-N-(3-chloroquinoxalin-2-yl)benzenesulfonamide; Benzenesulfonamide, 4-fluoro-N-(3-chloro-2-quinoxalinyl)-; N-(3-Chloro-2-quinoxalinyl)-4-fluorobenzenesulfonamide; 488744-02-1; 4-Fluoro-N-(3-chloro-quinoxalin-2-yl)-benzenesulfonamide; 3-Chloro-N-(4-fluorophenylsulfonyl)quinoxalin-2-amine
EINECS	Contact for details

Quality Control

Our n-(3-Chloro-Quinoxalin-2-Yl)-4-Fluoro-Benzenesulfonamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available for every lot to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.