Description

Tricyclo[2.2.1.02,6]Heptane-1,3-Dicarboxylic Acid, 3-Amino- (9Ci) is a high-purity, functionalized norbornane derivative, serving as a critical chiral building block and advanced pharmaceutical intermediate. Its unique rigid, polycyclic structure and bifunctional nature (carboxylic acid and amino groups) make it invaluable for synthesizing complex molecules with precise stereochemistry and enhanced physicochemical properties. This compound is essential for R&D and production in pharmaceutical chemistry, agrochemical development, and advanced material science, where structural complexity and purity are paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its structural rigidity for improved target binding and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating sophisticated chiral ligands and organocatalysts used in asymmetric synthesis.
• Polymer & Material Science: Acts as a monomer or cross-linking agent for synthesizing high-performance polymers, resins, and specialty materials with tailored thermal and mechanical properties.
• Academic & Industrial R&D: A valuable tool for medicinal chemistry research, process chemistry development, and exploring new chemical entities in life sciences.
• Fine Chemical Production: Employed in the multi-step synthesis of complex fine chemicals and flavors & fragrances requiring specific stereochemical configurations.

Basic Information

Product Name	Tricyclo[2.2.1.02,6]Heptane-1,3-Dicarboxylic Acid, 3-Amino- (9Ci)
CAS No.	482377-92-4
Molecular Formula	C9H11NO4
Molecular Weight	197.19 g/mol
Synonyms	3-Aminonorbornane-1,3-dicarboxylic Acid; 3-Aminobicyclo[2.2.1]heptane-1,3-dicarboxylic Acid; 3-Amino-2,4-dicarboxynorbornane; 1,3-Dicarboxy-3-aminonorbornane; 3-Amino-1,3-dicarboxynorbornane; 3-Aminotricyclo[2.2.1.0²,⁶]heptane-1,3-dicarboxylic Acid; 3-Amino-2,4-norbornanedicarboxylic Acid
EINECS	Contact for details

Quality Control

Our Tricyclo[2.2.1.02,6]Heptane-1,3-Dicarboxylic Acid, 3-Amino- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for pharmaceutical and advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.