Description

Tricyclo[2.2.1.02,6]Heptane-1,3-Dicarboxylic Acid, 3-Amino-, (1R,2R,3S,4S,6S)- is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. Its rigid, polycyclic "norbornane-like" core and strategically positioned amino and dicarboxylic acid functional groups make it a versatile precursor for constructing complex molecular architectures. This compound is primarily utilized by pharmaceutical R&D and fine chemical manufacturers for developing novel active pharmaceutical ingredients (APIs), chiral ligands, and specialty polymers.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, particularly in areas requiring rigid, three-dimensional scaffolds.
• Chiral Ligand & Catalyst Synthesis: Serves as a foundational structure for creating enantioselective catalysts and auxiliaries used in asymmetric synthesis.
• Advanced Material Precursor: Used in the synthesis of specialty polymers and dendrimers with tailored thermal and mechanical properties.
• Chemical Biology & Proteomics: Employed as a molecular scaffold or linker in the design of chemical probes and bioconjugates.
• Academic & Industrial Research: A valuable compound for methodological development in organic chemistry and materials science.

Basic Information

Item	Detail
Product Name	Tricyclo[2.2.1.02,6]Heptane-1,3-Dicarboxylic Acid, 3-Amino-, (1R,2R,3S,4S,6S)-
CAS No.	482377-80-0
Molecular Formula	C10H13NO4
Molecular Weight	211.21 g/mol
Synonyms	(1R,2R,3S,4S,6S)-3-Aminotricyclo[2.2.1.02,6]heptane-1,3-dicarboxylic acid; (1R,2R,3S,4S,6S)-3-Amino-1,3-dicarboxytricyclo[2.2.1.02,6]heptane; 3-Aminobicyclo[2.2.1]heptane-2,5-dicarboxylic acid derivative; Chiral Norbornane Amino Diacid; Stereoisomer of 3-Aminotricyclo[2.2.1.02,6]heptane-1,3-dicarboxylic Acid
EINECS	Contact for details

Quality Control

Our Tricyclo[2.2.1.02,6]Heptane-1,3-Dicarboxylic Acid, 3-Amino-, (1R,2R,3S,4S,6S)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure high chemical and stereochemical purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic nature, store in a cool, dry place, ideally under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal purity and stability. Recommended storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.