Description

Tricyclo[2.2.1.02,6]Heptane-1,3-Dicarboxylic Acid, 3-Amino-, (1R,2R,3R,4S,6S)- is a high-purity, stereochemically defined chiral building block with the CAS number 482373-22-8. This compound is valued for its rigid, polycyclic structure and functional groups, making it a critical intermediate in advanced organic synthesis. It is primarily sought after by research institutions and pharmaceutical companies for the development of novel active pharmaceutical ingredients (APIs), complex ligands, and specialty polymers.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug molecules, particularly in central nervous system (CNS) and antiviral research.
• Asymmetric Catalyst Ligand Precursor: Used to develop novel chiral ligands for metal-catalyzed asymmetric reactions, enhancing enantioselectivity.
• Advanced Material Synthesis: Serves as a building block for high-performance polymers and resins with specific thermal and mechanical properties.
• Academic & Industrial Research: A valuable tool for methodological development in organic chemistry and the exploration of new chemical spaces.
• Peptidomimetics & Bioactive Molecule Design: Its constrained geometry mimics peptide turn structures, useful in designing enzyme inhibitors and receptor modulators.
• Agrochemical Intermediate: Potential use in the synthesis of novel, stereospecific herbicides or plant growth regulators.

Basic Information

Product Name	Tricyclo[2.2.1.02,6]Heptane-1,3-Dicarboxylic Acid, 3-Amino-, (1R,2R,3R,4S,6S)-
CAS No.	482373-22-8
Molecular Formula	C9H11NO4
Molecular Weight	197.19 g/mol
Synonyms	(1R,2R,3R,4S,6S)-3-Aminotricyclo[2.2.1.02,6]heptane-1,3-dicarboxylic acid; 3-Aminobicyclo[2.2.1]heptane-2,5-dicarboxylic acid (specific stereoisomer); endo-3-Aminonorbornane-2,5-dicarboxylic acid; (1R,2R,3R,4S,6S)-3-Amino-2,5-norbornanedicarboxylic acid; Chiral NBDA derivative; 3-Amino-2,5-norbornanedicarboxylic acid (stereopure); 482373-22-8
EINECS	Contact for details

Quality Control

Our Tricyclo[2.2.1.02,6]Heptane-1,3-Dicarboxylic Acid, 3-Amino-, (1R,2R,3R,4S,6S)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure high chemical and stereochemical purity suitable for sensitive synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.