Description

Spiro[Bicyclo[2.2.1]Heptane-2,2-Oxirane], 3,3-Dimethyl-, (1R,2R,4S)- (9Ci) is a high-purity, stereochemically defined spirocyclic oxirane derivative. This compound serves as a versatile and valuable chiral building block in advanced organic synthesis, enabling the construction of complex molecular architectures with precise three-dimensional control. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where its rigid spirocyclic structure can contribute to biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of specialty polymers and advanced organic materials with unique optical or mechanical properties.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic chemistry and for exploring new chemical spaces in discovery programs.

Basic Information

Item	Detail
Product Name	Spiro[Bicyclo[2.2.1]Heptane-2,2-Oxirane], 3,3-Dimethyl-, (1R,2R,4S)- (9Ci)
CAS No.	481660-33-7
Molecular Formula	C10H16O
Molecular Weight	152.23 g/mol
Synonyms	(1R,2R,4S)-3,3-Dimethylspiro[bicyclo[2.2.1]heptane-2,2'-oxirane]; (1R,2R,4S)-3,3-Dimethyl-2-oxaspiro[bicyclo[2.2.1]heptane-2,2'-oxirane]; Spiro[norbornane-2,2'-oxirane], 3,3-dimethyl-, (1R,2R,4S)-; Chiral Spirocyclic Oxirane; 3,3-Dimethylspiro[norbornane-2,2'-oxirane] (enantiomer); (1R,2R,4S)-rel-3,3-Dimethylspiro[bicyclo[2.2.1]heptane-2,2'-oxirane]; CAS 481660-33-7
EINECS	Contact for details

Quality Control

Our Spiro[Bicyclo[2.2.1]Heptane-2,2-Oxirane], 3,3-Dimethyl-, (1R,2R,4S)- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC and GC, to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with full analytical data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.