Description

o-(2-Bromoethyl)-L-Tyrosine Hcl is a specialized, non-natural amino acid derivative used as a critical building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceuticals and biochemical probes, particularly in targeted drug delivery and radiopharmaceutical applications. It is primarily needed by research institutions and pharmaceutical companies engaged in peptide modification, oncology research, and the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel tyrosine kinase inhibitors and other targeted therapeutic agents.
• Radiopharmaceutical Development: Used in the research and production of radiolabeled compounds for Positron Emission Tomography (PET) imaging and targeted radiotherapy.
• Peptide & Protein Modification: Enables site-specific alkylation and functionalization of peptides and proteins for biochemical studies and drug conjugation (e.g., Antibody-Drug Conjugates - ADCs).
• Biochemical Probe Synthesis: Serves as a building block for creating affinity labels and activity-based probes to study enzyme mechanisms and protein function.
• Organic Synthesis Research: A valuable reagent for academic and industrial research in medicinal chemistry and chemical biology for constructing complex molecular architectures.

Basic Information

Product Name	o-(2-Bromoethyl)-L-Tyrosine Hcl
CAS No.	481052-60-2
Molecular Formula	C₁₁H₁₅BrClNO₃
Molecular Weight	324.60 g/mol
Synonyms	L-Tyrosine, O-(2-bromoethyl)-, hydrochloride; (2S)-2-Amino-3-[4-(2-bromoethoxy)phenyl]propanoic acid hydrochloride; O-(2-Bromoethyl)tyrosine hydrochloride; 2-Bromoethyl-L-tyrosine HCl; BrETyr·HCl; ATE-Br hydrochloride; 4-(2-Bromoethoxy)-L-phenylalanine hydrochloride
EINECS	Contact for details

Quality Control

Our o-(2-Bromoethyl)-L-Tyrosine Hcl is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency suitable for research and development. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.