Description

Boc-(R)-3-Amino-3-(4-Fluoro-Phenyl)-Propionic Acid is a high-purity, non-natural amino acid derivative featuring a Boc-protected amine group and a fluorinated aromatic side chain. This compound is a critical chiral building block for the synthesis of complex bioactive molecules, offering precise stereochemical control. It is primarily utilized by pharmaceutical R&D and process chemistry teams in the development of peptide-based therapeutics, enzyme inhibitors, and other advanced drug candidates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of novel Active Pharmaceutical Ingredients (APIs), particularly for metabolic and neurological disorders.
• Peptidomimetics & PROTACs: Serves as a crucial component for constructing peptide-like molecules and Proteolysis Targeting Chimeras (PROTACs) due to its stable backbone and fluorinated aromatic ring.
• Chemical Biology Probes: Used in the development of labeled probes and inhibitors for studying enzyme mechanisms and protein-protein interactions.
• Asymmetric Synthesis: Employed as a starting material or auxiliary in catalytic asymmetric reactions to introduce chiral centers with high enantiomeric purity.
• Agrochemical Research: Acts as a precursor in the discovery of advanced crop protection agents with optimized activity profiles.

Basic Information

Product Name	Boc-(R)-3-Amino-3-(4-Fluoro-Phenyl)-Propionic Acid
CAS No.	479064-94-3
Molecular Formula	C₁₄H₁₈FNO₄
Molecular Weight	283.30 g/mol
Synonyms	(R)-3-((tert-Butoxycarbonyl)amino)-3-(4-fluorophenyl)propanoic acid; N-Boc-3-Amino-3-(4-fluorophenyl)-(R)-propionic Acid; Boc-D-4-F-Phe-OH; tert-Butyl (R)-3-amino-3-(4-fluorophenyl)propanoate; (R)-N-Boc-3-Amino-3-(4-fluoro-phenyl)propionic Acid; (R)-3-(Boc-amino)-3-(4-fluorophenyl)propanoic acid; BOC-(R)-3-AMINO-3-(4-FLUORO-PHENYL)-PROPIONIC ACID
EINECS	Contact for details

Quality Control

Our Boc-(R)-3-Amino-3-(4-Fluoro-Phenyl)-Propionic Acid is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure compliance with research and development standards. Certificates of Analysis (COA) detailing identity, purity, and specific impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.