Description

Hexamethylguanidinium Pentafluoroethanolate is a specialized, high-purity guanidinium salt derivative with unique reactivity and solubility properties. This compound matters as a powerful, non-nucleophilic base and phase-transfer catalyst, enabling critical reactions in advanced chemical synthesis where traditional bases fail. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require precise control over challenging synthetic pathways, such as fluorination reactions and the preparation of sensitive intermediates.

Application

• As a powerful, non-nucleophilic base in organic synthesis, particularly for deprotonation reactions.
• As a phase-transfer catalyst (PTC) in biphasic reaction systems to enhance reaction rates and yields.
• In the synthesis of fluorinated compounds and active pharmaceutical ingredients (APIs) where its stability is advantageous.
• For the preparation of specialty polymers and advanced materials requiring specific catalytic activity.
• In agrochemical research for developing novel crop protection agents.
• As a reagent in academic and industrial R&D for exploring new synthetic methodologies.

Basic Information

Product Name	Hexamethylguanidinium Pentafluoroethanolate
CAS No.	479024-70-9
Molecular Formula	C9H19F5N3O
Molecular Weight	295.26 g/mol
Synonyms	1,1,3,3,3-Hexamethylguanidinium 2,2,2-Trifluoro-1-(trifluoromethyl)ethoxide; Hexamethylguanidinium 1,1,1,3,3,3-Hexafluoro-2-propoxide; HMG-PFE; Pentafluoroethanol Hexamethylguanidinium Salt; Guanidine, N,N,N',N',N'',N''-hexamethyl-, salt with 1,1,1,3,3,3-hexafluoro-2-propanol (1:1); HMGN⁺ CF3C(O-)CF3
EINECS	Contact for details

Quality Control

Our Hexamethylguanidinium Pentafluoroethanolate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and Karl Fischer titration, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.