Description

10H-Phenoxazine-1-Carboxylic Acid, 7-Chloro-3-[(Methylamino)Sulfonyl]-8-(Trifluoromethyl)- is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a unique phenoxazine scaffold functionalized with chlorotrifluoromethyl and methylaminosulfonyl groups. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers targeting innovative therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its complex, multi-functionalized heterocyclic core.
• Agrochemical Development: Serves as a precursor in the research and synthesis of new-generation pesticides and herbicides, leveraging its halogenated structure.
• Material Science Research: Investigated as a potential monomer or dopant for advanced organic electronic materials, such as OLEDs or conductive polymers.
• Biochemical Probe Synthesis: Utilized to create specialized probes and inhibitors for studying enzyme mechanisms and biological pathways in academic and industrial settings.

Basic Information

Item	Details
Product Name	10H-Phenoxazine-1-Carboxylic Acid, 7-Chloro-3-[(Methylamino)Sulfonyl]-8-(Trifluoromethyl)-
CAS No.	478298-95-2
Molecular Formula	C15H10ClF3N2O4S
Molecular Weight	406.76 g/mol
Synonyms	7-Chloro-3-[(methylamino)sulfonyl]-8-(trifluoromethyl)-10H-phenoxazine-1-carboxylic acid; 478298-95-2; Phenoxazine-1-carboxylic acid, 7-chloro-3-[(methylamino)sulfonyl]-8-(trifluoromethyl)-10H-; 7-Chloro-8-trifluoromethyl-3-methylaminosulfonyl-phenoxazine-1-carboxylic acid; 3-(Methylsulfamoyl)-7-chloro-8-(trifluoromethyl)-10H-phenoxazine-1-carboxylic acid
EINECS	Contact for details

Quality Control

Our 10H-Phenoxazine-1-Carboxylic Acid, 7-Chloro-3-[(Methylamino)Sulfonyl]-8-(Trifluoromethyl)- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. Handle and store in accordance with all applicable local and international regulations.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.