Description

2,2'-((1S,2S)-1,2-Cyclohexanediylbis((E)-nitrilomethylylidene))bis(4,6-di-tert-butylphenol) is a high-purity, chiral salen-type ligand with significant utility in asymmetric catalysis and materials science. Its value lies in its ability to form stable complexes with various transition metals, enabling highly selective and efficient chemical transformations. This compound is essential for researchers and manufacturers in the pharmaceutical, fine chemical, and advanced polymer industries who require precise stereochemical control in their synthesis processes.

Application

• Asymmetric Catalysis: As a key chiral ligand for metal-catalyzed reactions including epoxidation, cyclopropanation, and Diels-Alder reactions.
• Pharmaceutical Intermediates: Synthesis of enantiomerically pure active pharmaceutical ingredients (APIs) and complex drug candidates.
• Polymer Stabilization: Potential application as a specialized antioxidant or metal deactivator in high-performance polymers.
• Material Science Research: Building block for the development of chiral metal-organic frameworks (MOFs) and functional materials.
• Organic Synthesis: Use in academic and industrial R&D for developing novel synthetic methodologies.
• Analytical Chemistry: Potential use as a chiral selector or resolving agent in chromatography.

Basic Information

Product Name	2,2'-((1S,2S)-1,2-Cyclohexanediylbis((E)-nitrilomethylylidene))bis(4,6-di-tert-butylphenol)
CAS No.	478282-27-8
Molecular Formula	C40H60N2O2
Molecular Weight	600.92 g/mol
Synonyms	(1S,2S)-N,N'-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediamine; (1S,2S)-(-)-1,2-Diaminocyclohexane-N,N'-bis(3,5-di-tert-butylsalicylidene); (S,S)-Jacobsen's Ligand (tert-butyl variant); (S,S)-(-)-N,N'-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediamine; (S,S)-H2[salen-t-Bu]; Chiral Salen Ligand (t-Bu); (1S,2S)-Cyclohexanediamino-N,N'-bis(2,4-di-tert-butylphenol)
EINECS	Contact for details

Quality Control

Our 2,2'-((1S,2S)-1,2-Cyclohexanediylbis((E)-nitrilomethylylidene))bis(4,6-di-tert-butylphenol) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chiral purity and chemical consistency, meeting the stringent requirements for research and process development. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, Chiral HPLC) are provided to guarantee traceability and support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.