Description

5-(5,6,7,8-Tetrahydro-1,8-Naphthyridin-2-Yl)Pentanoic Acid is a high-purity, advanced pharmaceutical intermediate with a unique fused bicyclic structure. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting neurological and cardiovascular pathways. It is essential for research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in novel drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly for central nervous system (CNS) and cardiovascular therapeutics.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its naphthyridine scaffold.
• Process Chemistry Development: Serves as a critical starting material or intermediate in scaling up API synthesis under Good Manufacturing Practice (GMP) conditions.
• Bioconjugation & Probe Synthesis: The carboxylic acid functional group enables conjugation to other molecules, peptides, or labels for creating biochemical probes.
• Academic & Industrial R&D: Fundamental research in heterocyclic chemistry and the development of new synthetic methodologies.

Basic Information

Product Name	5-(5,6,7,8-Tetrahydro-1,8-Naphthyridin-2-Yl)Pentanoic Acid
CAS No.	478055-40-2
Molecular Formula	C15H20N2O2
Molecular Weight	260.33 g/mol
Synonyms	5-(5,6,7,8-Tetrahydro-1,8-naphthyridin-2-yl)pentanoic acid; 2-(5-Carboxypentyl)-5,6,7,8-tetrahydro-1,8-naphthyridine; 5-(1,8-Naphthyridin-2-yl)pentanoic acid, 5,6,7,8-tetrahydro-; 5-(5,6,7,8-Tetrahydro[1,8]naphthyridin-2-yl)valeric acid; 478055-40-2 (CAS); Tetrahydro-naphthyridine pentanoic acid derivative
EINECS	Contact for details

Quality Control

Our 5-(5,6,7,8-Tetrahydro-1,8-Naphthyridin-2-Yl)Pentanoic Acid is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.