Description

2-(Trifluoromethyl)-1H-1,3-Benzimidazole-4,7-Dione is a specialized heterocyclic organic compound featuring a benzimidazole core substituted with a trifluoromethyl group and quinone functionalities. This unique structure makes it a valuable high-purity intermediate for advanced chemical synthesis, particularly in the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily sought by pharmaceutical R&D teams, agrochemical innovators, and specialty chemical manufacturers for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting specific enzyme inhibitors or receptor modulators.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, or pesticides where the trifluoromethyl group enhances biological activity and stability.
• Material Science: Serves as a precursor for organic electronic materials, such as components for OLEDs or conductive polymers, due to its electron-deficient quinone structure.
• Dye and Pigment Synthesis: Acts as an intermediate for creating specialized heterocyclic dyes with specific light-absorption or fluorescence properties.
• Ligand and Catalyst Development: Utilized in organometallic chemistry to create novel ligands for catalysis in asymmetric synthesis or cross-coupling reactions.
• Academic and Industrial R&D: Employed in research laboratories for methodological studies and exploring new chemical reactions involving fluorinated heterocycles.

Basic Information

Product Name	2-(Trifluoromethyl)-1H-1,3-Benzimidazole-4,7-Dione
CAS No.	478050-30-5
Molecular Formula	C8H3F3N2O2
Molecular Weight	216.12 g/mol
Synonyms	2-(Trifluoromethyl)-1H-benzimidazole-4,7-dione; 4,7-Dioxo-2-(trifluoromethyl)-1H-benzimidazole; 1H-1,3-Benzimidazole-4,7-dione, 2-(trifluoromethyl)-; 2-Trifluoromethyl-1H-benzimidazole-4,7-dione; 2-(Trifluoromethyl)-4,7-dihydroxybenzimidazole (tautomer); TFBD; Trifluoromethyl benzimidazoledione
EINECS	Contact for details

Quality Control

Our production of 2-(Trifluoromethyl)-1H-1,3-Benzimidazole-4,7-Dione adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and industrial use. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as identity, assay, and impurity profiles. Our quality systems are designed to support cGMP compliance for pharmaceutical applications, and we can accommodate custom purity specifications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep away from incompatible materials such as strong bases and fluorides.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.