Description

(E)-3-(4-Methoxyanilino)-1-[4-Methyl-2-(3-Pyridinyl)-1,3-Thiazol-5-Yl]-2-Propen-1-One is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound matters as a critical building block in the synthesis of novel therapeutic agents, offering researchers and manufacturers a reliable and well-characterized starting material. It is primarily needed by the pharmaceutical and biotechnology industries for research and development, particularly in the areas of kinase inhibitor and targeted cancer therapy discovery.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potential drug candidates, especially kinase inhibitors.
• Biochemical Research: Used as a reference standard or a probe compound in enzymatic assays and target validation studies.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations engaged in custom synthesis and process development for client projects.
• Academic Research: Utilized in university and institutional labs for investigating new synthetic pathways and biological mechanisms.

Basic Information

Product Name	(E)-3-(4-Methoxyanilino)-1-[4-Methyl-2-(3-Pyridinyl)-1,3-Thiazol-5-Yl]-2-Propen-1-One
CAS No.	478041-29-1
Molecular Formula	C19H17N3O2S
Molecular Weight	351.42 g/mol
Synonyms	(E)-3-(4-Methoxyphenylamino)-1-(4-methyl-2-(pyridin-3-yl)thiazol-5-yl)prop-2-en-1-one; 3-(4-Methoxyanilino)-1-[4-methyl-2-(3-pyridinyl)-1,3-thiazol-5-yl]-2-propen-1-one; (E)-1-(4-Methyl-2-(pyridin-3-yl)thiazol-5-yl)-3-(4-methoxyphenylamino)prop-2-en-1-one; 478041-29-1; 3-Pyridinylthiazole propenone derivative; Kinase inhibitor intermediate SC-1
EINECS	Contact for details

Quality Control

Our (E)-3-(4-Methoxyanilino)-1-[4-Methyl-2-(3-Pyridinyl)-1,3-Thiazol-5-Yl]-2-Propen-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with complete analytical data are available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.