Description

2(1H)-Quinolinone, 3,4-Dihydro-6-Hydroxy-4,4,7,8-Tetramethyl- (9Ci) is a high-purity, synthetically derived quinolinone derivative, serving as a critical advanced intermediate for complex organic synthesis. Its value lies in its unique tetramethyl-substituted dihydroquinolinone structure, which provides a versatile scaffold for constructing molecules with specific steric and electronic properties. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry research targeting central nervous system (CNS) disorders, anti-inflammatory agents, and other therapeutic areas.
• Agrochemical Synthesis: Used as a precursor in the development of new-generation pesticides, herbicides, and plant growth regulators, leveraging its heterocyclic core for bioactivity.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a starting material or dopant in the creation of electron-transporting or host materials for OLED displays and lighting due to its potential photophysical properties.
• Coordination Chemistry & Ligand Design: The hydroxyquinolinone moiety can act as a chelating ligand for metal ions, useful in catalysis, sensors, and metal-organic frameworks (MOFs).
• Dye & Pigment Intermediate: Employed in the synthesis of specialized heterocyclic dyes and pigments for high-performance applications.
• Academic & Industrial R&D: A valuable reagent for method development and exploring new chemical reactions in synthetic organic chemistry laboratories.

Basic Information

Product Name	2(1H)-Quinolinone, 3,4-Dihydro-6-Hydroxy-4,4,7,8-Tetramethyl- (9Ci)
CAS No.	478010-83-2
Molecular Formula	C₁₃H₁₇NO₂
Molecular Weight	219.28 g/mol
Synonyms	6-Hydroxy-4,4,7,8-tetramethyl-3,4-dihydro-2(1H)-quinolinone; 4,4,7,8-Tetramethyl-3,4-dihydro-6-hydroxy-2(1H)-quinolinone; 3,4-Dihydro-6-hydroxy-4,4,7,8-tetramethyl-2(1H)-quinolinone; Tetramethyl Dihydroxyquinolinone; TMHQ; Contact for additional trade names and abbreviations.
EINECS	Contact for details

Quality Control

Our 2(1H)-Quinolinone, 3,4-Dihydro-6-Hydroxy-4,4,7,8-Tetramethyl- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.