Description

4H-Inden-4-One,1,2,5,6,7,7A-Hexahydro-6-Methyl-,(6S,7Ar)-(9Ci) is a high-purity, stereochemically defined advanced pharmaceutical intermediate. This compound is valued for its complex, fused-ring structure which serves as a critical chiral building block in modern organic synthesis. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder targets. Our supply ensures consistent quality and reliable availability for critical R&D and scale-up processes.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug candidates, especially for neurological and metabolic diseases.
• Asymmetric Synthesis: Utilized as a sophisticated starting material or intermediate in catalytic asymmetric reactions to introduce specific stereocenters.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Process Chemistry Development: Used in the optimization and scale-up of synthetic routes for new chemical entities (NCEs).
• Academic Research: Employed in universities and research institutes for methodological studies in organic and heterocyclic chemistry.
• Fine Chemical Production: Incorporated into the manufacture of specialty chemicals requiring high stereochemical purity.

Basic Information

Product Name	4H-Inden-4-One,1,2,5,6,7,7A-Hexahydro-6-Methyl-,(6S,7Ar)-(9Ci)
CAS No.	477959-78-7
Molecular Formula	C10H14O
Molecular Weight	150.22 g/mol
Synonyms	(6S,7aR)-1,2,5,6,7,7a-Hexahydro-6-methyl-4H-inden-4-one; (6S,7aR)-6-Methyl-1,2,5,6,7,7a-hexahydro-4H-inden-4-one; 6-Methyl-1,2,5,6,7,7a-hexahydro-4H-inden-4-one (6S,7aR)-; Hexahydro-6-methyl-4H-inden-4-one (stereo); CAS 477959-78-7; Advanced Chiral Indanone Derivative; Chiral Fused-Ring Ketone Intermediate
EINECS	Contact for details

Quality Control

Our 4H-Inden-4-One,1,2,5,6,7,7A-Hexahydro-6-Methyl-,(6S,7Ar)-(9Ci) is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and stereochemical integrity, meeting the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) detailing purity (typically by HPLC), chiral purity, and impurity profiles are provided with each shipment. We support compliance with relevant guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). The compound may be sensitive to prolonged exposure to air and moisture; keep container tightly sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.