Description

2-(4-Hydroxy-Phenyl)-7,8-Dihydro-6H-Quinazolin-5-One is a high-purity, synthetically derived quinazolinone derivative, serving as a critical pharmaceutical intermediate and research chemical. Its molecular structure makes it a valuable building block for the development of novel active pharmaceutical ingredients (APIs) and for advanced chemical synthesis. This compound is primarily utilized by pharmaceutical R&D teams, contract research organizations (CROs), and fine chemical manufacturers engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new quinazolinone-based therapeutics.
• Chemical Synthesis: Serves as a versatile scaffold for constructing more complex heterocyclic compounds in academic and industrial laboratories.
• Reference Standard: Employed as an analytical standard for quality control and method validation in pharmaceutical manufacturing.
• Biochemical Research: Investigated for its potential biological activity and enzyme inhibition properties in biochemical assays.

Basic Information

Product Name	2-(4-Hydroxy-Phenyl)-7,8-Dihydro-6H-Quinazolin-5-One
CAS No.	477870-20-5
Molecular Formula	C₁₅H₁₂N₂O₂
Molecular Weight	252.27 g/mol
Synonyms	2-(4-Hydroxyphenyl)-7,8-dihydro-6H-quinazolin-5-one; 5(6H)-Quinazolinone, 2-(4-hydroxyphenyl)-7,8-dihydro-; 2-(4-Hydroxy-phenyl)-7,8-dihydro-5H-quinazolin-5-one; 477870-20-5; Quinazolin-5-one, 2-(4-hydroxyphenyl)-7,8-dihydro-6H-
EINECS	Contact for details

Quality Control

Our 2-(4-Hydroxy-Phenyl)-7,8-Dihydro-6H-Quinazolin-5-One is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications and can provide documentation to meet rigorous audit requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.