Description

4-Chloro-N'-[2-(Trifluoromethyl)-4-Quinazolinyl]Benzenecarbohydrazide is a high-purity, advanced pharmaceutical intermediate characterized by its unique quinazoline and hydrazide functional groups. This compound matters for its critical role in the research and development of novel therapeutic agents, particularly in oncology and targeted drug discovery. Pharmaceutical R&D laboratories and fine chemical manufacturers need this precise chemical building block to synthesize and screen new drug candidates with potential kinase-inhibiting activity.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel quinazoline-based drug candidates for targeted cancer therapies.
• Kinase Inhibitor Research: Used in medicinal chemistry programs to develop and test potential inhibitors for various kinase targets implicated in disease pathways.
• Chemical Biology Probes: Serves as a core structure for creating molecular probes to study specific enzyme functions and cellular signaling processes.
• Agrochemical Research: Investigated as a precursor for developing new active ingredients with herbicidal or fungicidal properties.
• Material Science: Potential monomer or additive in the development of specialized polymers and advanced organic materials.

Basic Information

Product Name	4-Chloro-N'-[2-(Trifluoromethyl)-4-Quinazolinyl]Benzenecarbohydrazide
CAS No.	477867-50-8
Molecular Formula	C₁₆H₁₀ClF₃N₄O
Molecular Weight	366.73 g/mol
Synonyms	4-Chloro-N'-[2-(trifluoromethyl)quinazolin-4-yl]benzohydrazide; Benzenecarbohydrazide, 4-chloro-N'-[2-(trifluoromethyl)-4-quinazolinyl]-; 4-Chloro-N'-(2-trifluoromethylquinazolin-4-yl)benzohydrazide; CAS 477867-50-8; 2-(Trifluoromethyl)-4-quinazolinyl 4-chlorobenzohydrazone; 4-Chlorobenzoic acid [2-(trifluoromethyl)-4-quinazolinyl]hydrazide
EINECS	Contact for details

Quality Control

Our 4-Chloro-N'-[2-(Trifluoromethyl)-4-Quinazolinyl]Benzenecarbohydrazide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.