Description

Methyl 4-[(4-Cyanoanilino)Methylene]-2-Methyl-5-Oxo-4,5-Dihydro-1H-Pyrrole-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate with the CAS number 477865-63-7. This compound is a critical building block in the synthesis of complex heterocyclic molecules, offering significant value in research and development for novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel pyrrole and pyrrolidine-based drug candidates targeting various therapeutic areas.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Organic Synthesis Building Block: Employed in the construction of complex heterocyclic frameworks due to its reactive methylene and carbonyl functionalities.
• Agrochemical Development: Potential intermediate for research into new crop protection agents and pesticides.
• Material Science Research: Investigated for the development of organic electronic materials or specialty dyes and pigments.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical and chemical industry clients.

Basic Information

Product Name	Methyl 4-[(4-Cyanoanilino)Methylene]-2-Methyl-5-Oxo-4,5-Dihydro-1H-Pyrrole-3-Carboxylate
CAS No.	477865-63-7
Molecular Formula	C16H15N3O3
Molecular Weight	297.31 g/mol
Synonyms	Methyl 4-[(4-cyanoanilino)methylene]-2-methyl-5-oxo-4,5-dihydro-1H-pyrrole-3-carboxylate; 4-[(4-Cyanoanilino)methylene]-2-methyl-5-oxo-4,5-dihydro-1H-pyrrole-3-carboxylic acid methyl ester; 1H-Pyrrole-3-carboxylic acid, 4,5-dihydro-4-[(4-cyanophenyl)amino]methylene]-2-methyl-5-oxo-, methyl ester; CAS 477865-63-7; Pyrrole-3-carboxylate intermediate; 4-Cyanoanilino methylene pyrrole ester.
EINECS	Contact for details

Quality Control

Our Methyl 4-[(4-Cyanoanilino)Methylene]-2-Methyl-5-Oxo-4,5-Dihydro-1H-Pyrrole-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.