Description

7-[1-(3-Fluorophenoxy)Ethyl][1,2,4]Triazolo[1,5-A]Pyrimidin-2-Amine is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused heterocyclic structure. This compound is of significant commercial importance for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular design. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of new drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel triazolopyrimidine-based drug candidates, potentially for antiviral, anticancer, or central nervous system (CNS) applications.
• Agrochemical Research: Serves as a key scaffold for developing new generation pesticides and herbicides, leveraging its heterocyclic core for biological activity.
• Chemical Biology Probe: Used in academic and industrial research to study enzyme inhibition and protein-ligand interactions due to its specific molecular architecture.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization studies for the commercial production of complex molecules.
• Custom Synthesis Building Block: Provided to contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.

Basic Information

Product Name	7-[1-(3-Fluorophenoxy)Ethyl][1,2,4]Triazolo[1,5-A]Pyrimidin-2-Amine
CAS No.	477865-03-5
Molecular Formula	C14H12FN5O
Molecular Weight	285.28 g/mol
Synonyms	7-[1-(3-Fluorophenoxy)ethyl]-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine; 2-Amino-7-[1-(3-fluorophenoxy)ethyl][1,2,4]triazolo[1,5-a]pyrimidine; CAS 477865-03-5; 7-(1-(3-Fluorophenoxy)ethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine; [1,2,4]Triazolo[1,5-a]pyrimidin-2-amine, 7-[1-(3-fluorophenoxy)ethyl]-; 477865-03-5
EINECS	Contact for details

Quality Control

Every batch of 7-[1-(3-Fluorophenoxy)Ethyl][1,2,4]Triazolo[1,5-A]Pyrimidin-2-Amine is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Specifications can be tailored to meet the stringent requirements of cGMP and other relevant regulatory frameworks for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere if necessary and opened only in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.