Description

7-[1-(2,4-Difluorophenoxy)Ethyl][1,2,4]Triazolo[1,5-A]Pyrimidin-2-Amine is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular frameworks. It is essential for research institutions and pharmaceutical manufacturers engaged in the development of new drug candidates, agrochemicals, and specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-infective therapies.
• Agrochemical Research: Serves as a core structure for developing new generation pesticides and herbicides with enhanced efficacy.
• Chemical Biology & Proteomics: Used as a specialized scaffold or ligand in the study of enzyme inhibition and protein-ligand interactions.
• Material Science: Potential application in the development of organic electronic materials due to its conjugated triazolopyrimidine core.
• Academic & R&D: Critical for medicinal chemistry research in universities and contract research organizations (CROs) for structure-activity relationship (SAR) studies.

Basic Information

Product Name	7-[1-(2,4-Difluorophenoxy)Ethyl][1,2,4]Triazolo[1,5-A]Pyrimidin-2-Amine
CAS No.	477864-98-5
Molecular Formula	C14H12F2N6O
Molecular Weight	318.28 g/mol
Synonyms	7-[1-(2,4-Difluorophenoxy)ethyl]-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine; 2-Amino-7-[1-(2,4-difluorophenoxy)ethyl][1,2,4]triazolo[1,5-a]pyrimidine; CAS 477864-98-5; 7-(1-(2,4-Difluorophenoxy)ethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine; [1,2,4]Triazolo[1,5-a]pyrimidin-2-amine, 7-[1-(2,4-difluorophenoxy)ethyl]-; DFEP-TAP Amine
EINECS	Contact for details

Quality Control

Our 7-[1-(1-(2,4-Difluorophenoxy)Ethyl][1,2,4]Triazolo[1,5-A]Pyrimidin-2-Amine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.