Description

1-(4-Fluorophenyl)-3-[(4-Methylphenyl)Sulfonyl]-1-Propanone is a high-value, specialized organic intermediate characterized by its distinct sulfonyl and fluorophenyl functional groups. This compound is critical for research and development in advanced organic synthesis, particularly in constructing complex molecular architectures. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers for the development of novel active pharmaceutical ingredients (APIs) and other performance chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Research: Used in the development of new-generation herbicides and fungicides, where the fluorine atom and sulfone group can enhance biological activity and environmental stability.
• Material Science Precursor: Acts as a monomer or cross-linking agent in the research of advanced polymers with specific thermal or optical properties.
• Organic Synthesis Reagent: Employed in academic and industrial laboratories for methodology development, such as in sulfonylation reactions or as a substrate for catalytic C-H functionalization studies.
• Liquid Crystal & OLED Material Development: Investigated as a core component or intermediate for creating novel organic electronic materials due to its rigid, conjugated structure.

Basic Information

Product Name	1-(4-Fluorophenyl)-3-[(4-Methylphenyl)Sulfonyl]-1-Propanone
CAS No.	477334-53-5
Molecular Formula	C16H15FO3S
Molecular Weight	306.35 g/mol
Synonyms	1-Propanone, 1-(4-fluorophenyl)-3-[(4-methylphenyl)sulfonyl]-; 3-(p-Tolylsulfonyl)-1-(4-fluorophenyl)-1-propanone; 1-(4-Fluorophenyl)-3-(tosyl)propan-1-one; 3-(4-Methylbenzenesulfonyl)-1-(4-fluorophenyl)propan-1-one; p-Tolyl 4-fluorophenacyl sulfone; 4-Fluorophenyl 3-(p-tolylsulfonyl)propyl ketone; FPP-Tosyl ketone
EINECS	Contact for details

Quality Control

Our production of 1-(4-Fluorophenyl)-3-[(4-Methylphenyl)Sulfonyl]-1-Propanone adheres to stringent quality management protocols. Every batch is analyzed using advanced chromatographic and spectroscopic techniques (HPLC, GC, NMR, IR) to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality system is designed to support cGMP and ISO standards for traceability and reliability, making it suitable for demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and contamination. Store away from incompatible materials such as strong oxidizing agents, strong bases, and strong reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.