Description

3-[(4-Fluorophenyl)Sulfonyl]-1-(4-Methoxyphenyl)-1-Propanone is a high-purity sulfone-based organic intermediate of significant importance in advanced chemical synthesis. Its unique molecular structure, featuring both fluorophenyl and methoxyphenyl moieties, makes it a versatile building block for the development of complex active pharmaceutical ingredients (APIs) and specialty chemicals. This compound is primarily sought by R&D and production teams in the pharmaceutical, agrochemical, and material science industries for creating novel compounds with targeted properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Serves as a building block for developing new-generation herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Material Science Research: Used in the development of advanced polymers, liquid crystals, and organic electronic materials due to its sulfone linkage and aromatic systems.
• Chemical Research & Development: A valuable scaffold for medicinal chemistry and process chemistry for structure-activity relationship (SAR) studies and route scouting.
• Fine Chemical Production: Employed in the custom synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	3-[(4-Fluorophenyl)Sulfonyl]-1-(4-Methoxyphenyl)-1-Propanone
CAS No.	477334-51-3
Molecular Formula	C16H15FO4S
Molecular Weight	322.35 g/mol
Synonyms	1-(4-Methoxyphenyl)-3-[(4-fluorophenyl)sulfonyl]propan-1-one; 3-(4-Fluorobenzenesulfonyl)-1-(4-methoxyphenyl)propan-1-one; 4-Fluoro-β-oxo-β-(4-methoxyphenyl)benzenepropanesulfonic acid sulfone; 4-Methoxyphenyl 4-fluorophenyl sulfone propanone; (4-Methoxyphenyl)[3-(4-fluorophenyl)sulfonyl]propyl ketone; 4-Fluoro-β-(4-methoxyphenyl)-β-oxobenzenepropanesulfonic acid sultone derivative; Propiophenone, 3-[(4-fluorophenyl)sulfonyl]-1-(4-methoxyphenyl)-
EINECS	Contact for details

Quality Control

Our production of 3-[(4-Fluorophenyl)Sulfonyl]-1-(4-Methoxyphenyl)-1-Propanone adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed specifications for every shipment, supporting your quality assurance and regulatory compliance needs. Our facilities operate under cGMP principles suitable for pharmaceutical intermediate manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.