Description

7-Quinolinecarboxylic Acid, 4-[5,6-Dihydro-2-(6-Methyl-2-Pyridinyl)-4H-Pyrrolo[1,2-B]Pyrazol-3-Yl]-, Methyl Ester is a high-purity, complex heterocyclic compound with the CAS number 476475-45-3. This advanced pharmaceutical intermediate is valued for its precise molecular architecture, which serves as a critical building block in modern drug discovery and development. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the synthesis of novel therapeutic agents, particularly in oncology and other specialized therapeutic areas.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs).
• Drug Discovery: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Oncology Research: Serves as a core scaffold in the synthesis of potential kinase inhibitors and other targeted cancer therapies.
• Chemical Synthesis: Employed in advanced organic synthesis to construct complex fused heterocyclic systems.
• Biochemical Research: Utilized as a reference standard or probe in biochemical and pharmacological assays.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	7-Quinolinecarboxylic Acid, 4-[5,6-Dihydro-2-(6-Methyl-2-Pyridinyl)-4H-Pyrrolo[1,2-B]Pyrazol-3-Yl]-, Methyl Ester
CAS No.	476475-45-3
Molecular Formula	C22H20N4O2
Molecular Weight	372.42 g/mol
Synonyms	Methyl 4-(5,6-dihydro-2-(6-methylpyridin-2-yl)-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinoline-7-carboxylate; 476475-45-3; UNII-9K8C8A6A6T; 4-[5,6-Dihydro-2-(6-methyl-2-pyridinyl)-4H-pyrrolo[1,2-b]pyrazol-3-yl]-7-quinolinecarboxylic acid methyl ester; 7-Quinolinecarboxylic acid, 4-[5,6-dihydro-2-(6-methyl-2-pyridinyl)-4H-pyrrolo[1,2-b]pyrazol-3-yl]-, methyl ester; Methyl 4-(2-(6-methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinoline-7-carboxylate
EINECS	Contact for details

Quality Control

Our 7-Quinolinecarboxylic Acid, 4-[5,6-Dihydro-2-(6-Methyl-2-Pyridinyl)-4H-Pyrrolo[1,2-B]Pyrazol-3-Yl]-, Methyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.