Description

6-Quinolinecarboxylic Acid, 4-[5,6-Dihydro-2-(2-Pyridinyl)-4H-Pyrrolo[1,2-B]Pyrazol-3-Yl]-, Methyl Ester is a high-purity, complex heterocyclic organic compound designed for advanced research and development. This compound serves as a critical pharmaceutical intermediate and building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought by pharmaceutical R&D teams, contract research organizations (CROs), and academic research institutions focused on medicinal chemistry and drug discovery.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for developing new chemical entities.
• Chemical Biology Probes: Serves as a core structure for developing molecular probes to study biological pathways and protein interactions.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and scale-up projects.
• Academic Research: Utilized in university and institutional labs for advanced organic synthesis and heterocyclic chemistry studies.
• Library Synthesis: A valuable scaffold for generating diverse compound libraries for high-throughput screening in drug discovery.

Basic Information

Product Name	6-Quinolinecarboxylic Acid, 4-[5,6-Dihydro-2-(2-Pyridinyl)-4H-Pyrrolo[1,2-B]Pyrazol-3-Yl]-, Methyl Ester
CAS No.	476475-43-1
Molecular Formula	C22H18N4O2
Molecular Weight	370.41 g/mol
Synonyms	4-[5,6-Dihydro-2-(pyridin-2-yl)-4H-pyrrolo[1,2-b]pyrazol-3-yl]quinoline-6-carboxylic acid methyl ester; Methyl 4-(5,6-dihydro-2-(pyridin-2-yl)-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinoline-6-carboxylate; 476475-43-1; Quinoline-6-carboxylic acid, 4-(5,6-dihydro-2-(2-pyridinyl)-4H-pyrrolo[1,2-b]pyrazol-3-yl)-, methyl ester
EINECS	Contact for details

Quality Control

Our 6-Quinolinecarboxylic Acid, 4-[5,6-Dihydro-2-(2-Pyridinyl)-4H-Pyrrolo[1,2-B]Pyrazol-3-Yl]-, Methyl Ester is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. Our quality system is designed to support cGMP requirements for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.